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Potentially harmful supplements

Allen Bowling and Thomas Stewart, Rocky Mountain MS Center, Colorado


  • Alfalfa: - immune-stimulating
  • Aloe: - may interact with steroids
  • Asian ginseng: - immune-stimulating, possibly fatigue-producing, may interact with steroids
  • Astragalus: - immune-stimulating
  • Bayberry: - may interact with steroids
  • Beta-carotene: - immune-stimulating, greater than 10,000 IU/day may produce toxic effects, avoid in smokers
  • Borage seed oil: - possible liver toxicity
  • Cat's claw: - immune-stimulating
  • Chamomile: - possibly fatigue-producing
  • Chaparral: - possible liver toxicity
  • Coenzyme Q10: - immune-stimulating, may interact with warfarin (Coumadin)
  • Comfrey: - possible liver toxicity
  • DHEA: - possibly immune-stimulating
  • Echinacea: - immune-stimulating
  • Garlic: - immune-stimulating
  • Goldenseal: - possibly immune-stimulating, possibly fatigue-producing
  • Grapeseed extract: - possibly immune-stimulating
  • Kava-kava: - possible severe liver toxicity, possibly fatigue-producing
  • Licorice: - may interact with steroids
  • Lobelia: - multiple possible toxic effects
  • Melatonin: - possibly immune-stimulating
  • Niacin: - greater than 35 milligrams/day may produce toxic effects
  • Nettle: - possibly fatigue-producing
  • Oligomeric proanthocyanidins: - possibly immune-stimulating
  • Passionflower: - possibly fatigue-producing
  • Pycnogenol: - possibly immune-stimulating
  • Sage: - possibly fatigue-producing
  • St. John's wort: - possibly fatigue-producing
  • Selenium: - possibly immune-stimulating, greater than 200 micrograms/day may produce multiple toxic effects
  • Siberian ginseng: - immune-stimulating, possibly fatigue-producing
  • Valerian: - possibly fatigue-producing
  • Vitamin A: - immune-stimulating, greater than 10,000 IU/day may produce toxic effects, avoid in smokers
  • Vitamin B6: - greater than 50 milligrams/day may produce toxic effects
  • Vitamin C: - immune-stimulating, greater than 1,000 milligrams/day may produce toxic effects, may interact with warfarin (Coumadin)
  • Vitamin D: - greater than 2,000 IU/day may be harmful
  • Vitamin E: - immune-stimulating, may interact with warfarin (Coumadin)
  • Vitamin K: - may interact with warfarin (Coumadin)
  • Zinc: - possibly immune-stimulating, may cause copper deficiency

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